A complete case-based review of the essentials of pathophysiology – covering all major organs and systems

This trusted text introduces students to clinical medicine by reviewing the pathophysiologic basis of the signs and symptoms of 100 diseases commonly encountered in medical practice. Each chapter first describes normal function of a major organ or organ system, then turns attention to the pathology and disordered physiology, including the role of genetics, immunology, and infection in pathogenesis. Underlying disease mechanisms are described, along with their systems, signs, and symptoms, and the way these mechanisms themselves determine the most effective treatment.

The unique interweaving of physiological and pathological concepts will put students on the path towards thinking about signs and symptoms in terms of their pathologic basis, providing an understanding of the “whys” behind both illness and treatment.

Enriched by high-quality full-color illustrations
All chapters completely updated to reflect breakthroughs in the field, new classification of drugs, and the most recent publications